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found that circ_0000808 was upregulated in NSCLC cells, where it enhanced the expression of the Gln transporter SLC1A5 by interacting with miR1827, thereby promoting Gln metabolism and facilitating the progression of NSCLC ( ncRNAs also influence tumor Gln metabolism by modulating various signaling pathways ( Table 1 )

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Therefore, controlled release of BAPPs can be achieved to a certain extent by changing intrinsic characteristics such as thickness dissolution and kinetics of the mineral coating [235]